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What is Histone Lactylation in Cancer Therapy about?
This review article discusses the role of histone lactylation in cancer, highlighting its impact on immune evasion and therapy resistance through metabolic reprogramming. It emphasizes how lactylation alters the tumor microenvironment by influencing macrophage polarization and T cell exhaustion, suggesting its potential as a therapeutic target. The authors also address unresolved questions and propose strategies for exploiting lactylation pathways in combination therapies.
- Author
- 2314804532
- Language
- EN