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What is Targeted CO Delivery for Tumor Therapy about?

This study presents a novel enzyme-triggered carbon monoxide-releasing molecule (ET-CORM) designed for targeted tumor therapy, utilizing a biocompatible iron core and activated by the cancer-associated protease cathepsin B. The ET-CORM can be site-specifically conjugated to antibodies, allowing selective intracellular CO delivery to HER2-overexpressing cancer cells. This approach opens new possibilities for CO-based cancer treatments by enhancing the targeting capabilities of CO-releasing molecules.

Author

Ahmed

Language

EN