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Can I read Chemo-promiscuity of Alcohol Dehydrogenases: Reduction of Phenylacetaldoxime to the Alcohol on EtoBox?

Chemo-promiscuity of Alcohol Dehydrogenases: Reduction of Phenylacetaldoxime to the Alcohol by Bianca Ferreira-Silva; Iván Lavandera; Alexander Kern; Kurt Faber; Wolfgang Kroutil is a Chemistry article available to read on EtoBox.

What is Chemo-promiscuity of Alcohol Dehydrogenases: Reduction of Phenylacetaldoxime to the Alcohol about?

The reduction of phenylacetaldoxime was catalysed by alcohol dehydrogenases in the presence of NAD(P)H yielding finally the primary alcohol via the imine and aldehyde intermediates. This suggests that the hydride of the cofactor NAD(P)H is transferred to the N-atom of the oxime moiety and not to the carbon atom, as usual stated. This reaction represents the first example of a catalytic chemo-promiscuity of alcohol dehydrogenases.

Who reads Chemo-promiscuity of Alcohol Dehydrogenases: Reduction of Phenylacetaldoxime to the Alcohol?

It is typically read by researchers, students, and practitioners in Chemistry.

Author
Bianca Ferreira-Silva; Iván Lavandera; Alexander Kern; Kurt Faber; Wolfgang Kroutil
Publisher
Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0040-4020)
Published
2010
Language
EN
Field
Chemistry (Physical Sciences)

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