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Exploring the Efficacy of Psychotherapies for Depression: a Multiverse Meta-analysis by Plessen, Constantin Yves (author);Karyotaki, Eirini (author);Miguel, Clara (author);Ciharova, Marketa (author);Cuijpers, Pim (author) is a Psychology article available to read on EtoBox.

What is Exploring the Efficacy of Psychotherapies for Depression: a Multiverse Meta-analysis about?

## Background Hundreds of randomised controlled trials and dozens of meta-analyses have examined psychotherapies for depression—yet not all points in the same direction. Are these discrepancies a result of specific meta-analytical decisions or do most analytical strategies reaching the same conclusion? ## Objective We aim to solve these discrepancies by conducting a multiverse meta-analysis containing all possible meta-analyses, using all statistical methods. ## Study selection and analysis We searched four bibliographical databases (PubMed, EMBASE, PsycINFO and Cochrane Register of Controlled Trials), including studies published until 1 January 2022. We included all randomised controlled trials comparing psychotherapies with control conditions without restricting the type of psychotherapy, target group, intervention format, control condition and diagnosis. We defined all possible meta-analyses emerging from combinations of these inclusion criteria and estimated the resulting pooled effect sizes with fixed-effect, random-effects, 3-level, robust variance estimation, __p__-uniform and PET-PEESE (precision-effect test and precision-effect estimate with SE) meta-analysis models. This

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Author

Plessen, Constantin Yves (author);Karyotaki, Eirini (author);Miguel, Clara (author);Ciharova, Marketa (author);Cuijpers, Pim (author)

Publisher

BMJ

Published

2023

Language

EN

Field

Psychology (Social Sciences)