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Quantitative study of the susceptibility difference between trabecular bone and bone marrow: Computer simulations by S. Majumdar is a Medicine article available to read on EtoBox.

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## Abstract Inherent differences in tissue magnetic susceptibility produce inhomogeneities in the static magnetic field which give rise to an additional dephasing of the transverse magnetization in gradient‐echo images. The enhanced dephasing of the signal results in an increase of the apparent relaxation rate 1/__T__ and a corresponding decrease in signal intensity. These effects have been used to explain the regional loss of marrow signal intensity in the appendicular skeleton, where in the presence of trabecular bone in the proximal tibia there is an enhanced loss of signal compared to the tibial shaft where there is no trabeculation. It has been postulated that differences in tissue magnetic susceptibility arising due to the marrow‐trabeculae interface give rise to magnetic field inhomogeneities and a reduced __T__. In this study computer simulations are used to determine whether susceptibility differences comparable to that between trabecular bone and tissue relate to the reduction of tissue __T__ and whether the reduction in __T__ is also related to the concentration and magnitude of susceptibility differences. In addition the effects of the spatial distribution of these part

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Author
S. Majumdar
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0740-3194)
Published
1991
Language
EN
Field
Medicine (Health Sciences)