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Clinical Impact and Direct Costs of Nosocomial Respiratory Syncytial Virus Infections in the Neonatal Intensive Care Unit by Andreu Comas-García; José I. Aguilera-Martínez; Francisco J. Escalante-Padrón; Victoria Lima-Rogel; Luis M. Gutierrez-Mendoza; Daniel E. Noyola is a Medicine article available to read on EtoBox.

What is Clinical Impact and Direct Costs of Nosocomial Respiratory Syncytial Virus Infections in the Neonatal Intensive Care Unit about?

## Background: Nosocomial infections are a leading cause of morbidity, costs, and mortality in preterm newborns. most reports regarding nosocomial infections in neonatal intensive care units (nicu) are focused on bacterial infections and there is limited information regarding the impact of nosocomial viruses. the objective of this study was to assess the impact of nosocomial respiratory syncytial virus (rsv) infections in a nicu. ## Methods: This was a retrospective cohort design from a nicu in a general hospital in mexico. we included 24 newborn infants with nosocomial rsv infection and 24 infants without rsv matched by gestational age, birth weight, and the period of time of hospitalization. ## Results: Infants with nosocomial rsv infection had longer hospitalization duration (median 24 days vs. 13 days; p = .05), increased antibiotic use (45.8% vs. 8.3%; p = .003), more mechanical ventilation requirement (54.2% vs. 0.4%; p <.001), more frequent nosocomial infections (45.8% vs. 0%; p <.001), and higher hospitalization direct costs (median 3,587.20 usd vs. 1,123.60 usd; p = .001) after nosocomial rsv detection. ## Conclusions: Nosocomial rsv infections are associated to a signific

Who reads Clinical Impact and Direct Costs of Nosocomial Respiratory Syncytial Virus Infections in the Neonatal Intensive Care Unit?

Author

Andreu Comas-García; José I. Aguilera-Martínez; Francisco J. Escalante-Padrón; Victoria Lima-Rogel; Luis M. Gutierrez-Mendoza; Daniel E. Noyola

Publisher

Elsevier Science; Elsevier ; Mosby Inc.; Elsevier BV (ISSN 1527-3296)

Published

2020

Language

EN

Field

Medicine (Health Sciences)