Opening book details…
Can I read Applied Nano Bio Systems with Microfluidics and Biosensors for Three-dimensional Cell Culture on EtoBox?
Applied Nano Bio Systems with Microfluidics and Biosensors for Three-dimensional Cell Culture by A. Schober; U. Fernekorn; B. Lübbers; J. Hampl; F. Weise; G. Schlingloff; M. Gebinoga; M. Worgull; Mark Schneider; Caroline Augspurger; Christian Hildmann; Mario Kittler; Mary Donahue is a Engineering article available to read on EtoBox.
What is Applied Nano Bio Systems with Microfluidics and Biosensors for Three-dimensional Cell Culture about?
## Abstract Applications of nanotechnology and microtechnology lead to a field which could be called nanosystems integration. The next step is the development of nanobiotechnological systems, which could reflect the hierarchical organization of biological systems that utilise scales and laws of nature on all metric scales. As one example of such systems we present the design and construction of a new class of micro bioreactors. It has been shown that 3D culture systems reveal the __in vivo__ situation much better than the cultivation of 2D one cell type alone. For this purpose we have to construct and arrange fluidic devices and a cell‐biological environment in such a way, that living cells can survive in a three‐dimensional, organ‐like structure, enabled by technical devices. Such organ‐like cell structures may lead to new ways in medicinal chemistry for the determination of ADME/Tox (absorption‐distribution‐metabolism‐excretion and toxicity) properties of potential drugs. One part of the construction principle is the integration of sensors, preferable novel AlGaN/GaN nanosensors. The latter nanosensors offer the possibility to estimate reactions of cells attached to the sensor su
Who reads Applied Nano Bio Systems with Microfluidics and Biosensors for Three-dimensional Cell Culture?
It is typically read by researchers, students, and practitioners in Engineering.
- Author
- A. Schober; U. Fernekorn; B. Lübbers; J. Hampl; F. Weise; G. Schlingloff; M. Gebinoga; M. Worgull; Mark Schneider; Caroline Augspurger; Christian Hildmann; Mario Kittler; Mary Donahue
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Ltd.; Wiley (ISSN 0933-5137)
- Published
- 2011
- Language
- EN
- Field
- Engineering (Physical Sciences)