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Effects of Gender on Fetal Cortical Development: a Secondary Analysis of a Prospective Cross-sectional Study by Ilenia Mappa; Maria Chiara Marra; Maria Elena Pietrolucci; Jia Li Angela Lu; Daniele Di Mascio; Francesco D’Antonio; Giuseppe Rizzo is a Medicine article available to read on EtoBox.

What is Effects of Gender on Fetal Cortical Development: a Secondary Analysis of a Prospective Cross-sectional Study about?

## Abstract ## Objectives The primary objective was to evaluate the effects of fetal sex on fetal cortical development in low-risk pregnancies. Secondary objective was the evaluate the impact of gestational age. ## Methods This was a secondary analysis of a prospective cross-sectional study on low-risk fetuses undergoing fetal neurosonography between 19 and 34 weeks of gestation. The depth of Sylvian Fissure (SF), Parieto Occipital Fissure (POF) and Calcarine Fissure (CF) were evaluated and related to fetal sex. Neurosonographic variables were normalized for fetal head circumference and expressed as multiple of the median (MoM). ## Results A total of 344 fetuses were considered (173 male, 171 female). The baseline characteristic of the two groups were similar except a higher birthweight present in male fetuses (p=0.044). The depth SF (p=0.023) CF (p=0.014) and POF (p=0.046) showed significantly higher values in male fetuses when all the gestational age range was considered. However, when data were controlled for gestational age, these differences resulted significant only after 28 weeks. ## Conclusions Differences in cortical development related to gender occur after 28 weeks of ge

Who reads Effects of Gender on Fetal Cortical Development: a Secondary Analysis of a Prospective Cross-sectional Study?

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Author
Ilenia Mappa; Maria Chiara Marra; Maria Elena Pietrolucci; Jia Li Angela Lu; Daniele Di Mascio; Francesco D’Antonio; Giuseppe Rizzo
Publisher
Walter de Gruyter GmbH
Published
2023
Field
Medicine (Health Sciences)

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