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Diet- and Sex-related Changes of Gut Microbiota Composition and Functional Profiles After 4 Months of Weight Loss Intervention by Amanda Cuevas-Sierra; Ana Romo-Hualde; Paula Aranaz; Leticia Goni; Marta Cuervo; J. Alfredo Martínez; Fermín I. Milagro; José I. Riezu-Boj is a Medicine article available to read on EtoBox.
What is Diet- and Sex-related Changes of Gut Microbiota Composition and Functional Profiles After 4 Months of Weight Loss Intervention about?
## Purpose: Obesity has been related to intestinal dysbiosis and the modification of gut microbiota composition by dietary strategies becomes a promising strategy to help manage obesity. the aim of the current study was to evaluate the effect of two weight-loss diets on the composition and functional profile of gut microbiota. ## Methods: 55 men and 124 women with bmi > 25 kg/m were randomly assigned to moderately high-protein (mhp) or low-fat (lf) diet. differences in fecal bacteria abundance (based on 16 s rrna sequencing) between before and after 4 months of calorie restriction was analyzed using edger tool in microbiomeanalyst platform. bacterial functional profile was predicted using tax4fun and metagenomeseq analysis. significant kegg orthology (ko) terms were selected for the metabolomic study using chromatography. ## Results: After the intervention, mhp-men showed a significant decrease in negativicutes, selenomonadales, dielma and dielma fastidiosa. lf-men showed a significant increase in bacilli, lactobacillales, christensenellaceae, peptococcaceae, and streptococcaceae, peptococcus, streptococcus and christensenella, duncaniella dubosii\_cp039396\_93.49%, roseburia sp\_a
Who reads Diet- and Sex-related Changes of Gut Microbiota Composition and Functional Profiles After 4 Months of Weight Loss Intervention?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Amanda Cuevas-Sierra; Ana Romo-Hualde; Paula Aranaz; Leticia Goni; Marta Cuervo; J. Alfredo Martínez; Fermín I. Milagro; José I. Riezu-Boj
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)