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Development and Characterization of a Versatile Mini‐beam Collimator for Pre‐clinical Photon Beam Irradiation by Christina Stengl; Eric Arbes; Long‐Yang Jan Thai; Gernot Echner; José Vedelago; Jeannette Jansen; Oliver Jäkel; Joao Seco is a Medicine article available to read on EtoBox.
What is Development and Characterization of a Versatile Mini‐beam Collimator for Pre‐clinical Photon Beam Irradiation about?
Background: Interest in spatial fractionation radiotherapy has exponentially increased over the last decade as a significant reduction of healthy tissue toxicity was observed by mini-beam irradiation. Published studies, however, mostly use rigid mini-beam collimators dedicated to their exact experimental arrangement such that changing the setup or testing new mini-beam collimator configurations becomes challenging and expensive. Purpose: In this work, a versatile, low-cost mini-beam collimator was designed and manufactured for pre-clinical applications with X-ray beams. The mini-beam collimator enables variability of the full width at half maximum (FWHM), the center-to-center distance (ctc), the peak-to-valley dose ratio (PVDR), and the source-to-collimator distance (SCD). Methods: The mini-beam collimator is an in-house development, which was constructed of 10 × 40 mm 2 tungsten or brass plates. These metal plates were combined with 3D-printed plastic plates that can be stacked together in the desired order. A standard X-ray source was used for the dosimetric characterization of four different configurations of the collimator, including a combination of plastic plates of 0.5, 1, o
Who reads Development and Characterization of a Versatile Mini‐beam Collimator for Pre‐clinical Photon Beam Irradiation?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Christina Stengl; Eric Arbes; Long‐Yang Jan Thai; Gernot Echner; José Vedelago; Jeannette Jansen; Oliver Jäkel; Joao Seco
- Publisher
- Wiley
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)