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Prolactin Directly Stimulates Citrate Production and Mitochondrial Aspartate Aminotransferase of Prostate Epithelial Cells by R. B. Franklin; L. C. Costello is a Medicine article available to read on EtoBox.
What is Prolactin Directly Stimulates Citrate Production and Mitochondrial Aspartate Aminotransferase of Prostate Epithelial Cells about?
## Abstract Prolactin, in vitro, significantly increased citrate production, mAAT (mitochondrial aspartate aminotransferase) and pmAAT (precursor form of mAAT) activity of prostate epithelial cells derived from rat lateral prostate (LP) and pig prostate cultures. In contrast, prolactin had no effect on the cytosolic isozyme, cAAT. This prolactin effect appeared to be independent of testosterone. The phorbol ester TPA (12‐O‐tetradecanoyl‐phorbol‐13‐acetate) induced the same effects as prolactin thereby indicating the involvement of protein kinase C. This report demonstrates that prolactin directly regulates citrate production of prostate epithelial cells and the availability of an in vitro model to elucidate the mechanism of action of prolactin.
Who reads Prolactin Directly Stimulates Citrate Production and Mitochondrial Aspartate Aminotransferase of Prostate Epithelial Cells?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- R. B. Franklin; L. C. Costello
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0270-4137)
- Published
- 1990
- Language
- EN
- ISBN
- 9782990170109
- Field
- Medicine (Health Sciences)