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Engineering of Chitosan-derived nanoparticles to enhance antimicrobial activity against foodborne pathogen Escherichia coli O157:H7 by Garrido-Maestu, Alejandro; Ma, Zhengxin; Paik, Sae-Yeol-Rim; Chen, Nusheng; Ko, Sanghoon; Tong, Zhaohui; Jeong, KwangCheol Casey is a Materials Science article available to read on EtoBox.

What is Engineering of Chitosan-derived nanoparticles to enhance antimicrobial activity against foodborne pathogen Escherichia coli O157:H7 about?

Chitosan is an abundant and natural polymer derived from chitin, which presents a wide variety of properties, including antimicrobial activity. The raising of antibiotic resistant bacteria has increased the interest in finding alternatives to traditional antibiotics. Many studies have assessed the antimicrobial activity of chitosan itself, but a few have performed comparisons among different chitosan nanoparticle synthesis, which will be of particular interest for further applications. In this study, the effects of two types of cross-linking agents, sodium sulfate vs. tripolyphosphate, along with molecular weight (Mw) of chitosan, low vs. high Mw, and different sonication treatments, time and power, were assessed to determine the optimal conditions to enhance antimicrobial activity against bacterial pathogens. Physiochemical characteristics of the engineered chitosan nanoparticles were determined. It was observed that 20 min sonication time, low Mw of chitosan, Sodium sulfate as cross-linker, and particle size smaller than <300 nm, showed the greatest antimicrobial activity. Chitosan nanoparticles generated at this condition completely killed pathogenic E. coli O157:H7 without rais

Who reads Engineering of Chitosan-derived nanoparticles to enhance antimicrobial activity against foodborne pathogen Escherichia coli O157:H7?

It is typically read by researchers, students, and practitioners in Materials Science.

Author
Garrido-Maestu, Alejandro; Ma, Zhengxin; Paik, Sae-Yeol-Rim; Chen, Nusheng; Ko, Sanghoon; Tong, Zhaohui; Jeong, KwangCheol Casey
Publisher
Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0144-8617)
Published
2018
Language
EN
Field
Materials Science (Physical Sciences)

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