Opening book details…
Can I read Hyaluronic Acid Oligosaccharide-collagen Mineralized Product and Aligned Nanofibers with Enhanced Vascularization Properties in Bone Tissue Engineering on EtoBox?
Hyaluronic Acid Oligosaccharide-collagen Mineralized Product and Aligned Nanofibers with Enhanced Vascularization Properties in Bone Tissue Engineering by Liling Liu; Weibin Jia; Yuanmeng Zhou; Hang Zhou; Meng Liu; Min Li; Xiuli Zhang; Guofeng Gu; Zonggang Chen is a Materials Science article available to read on EtoBox.
What is Hyaluronic Acid Oligosaccharide-collagen Mineralized Product and Aligned Nanofibers with Enhanced Vascularization Properties in Bone Tissue Engineering about?
Considering the structural complexity of natural bone and the limitations of current treatment options, designing a biomimetic and functional tissue-engineered bone graft has been an urgent need for the replacement and regeneration of defected bone tissue. In light of the cell recruitment to the defect region, scaffold-guided bone tissue engineering has proven to be a viable strategy that is poised to deliver effective osseointegration and vascularization during bone remodeling. Herein, we provide an engineered bone scaffold based on aligned poly (lactic-co-glycolide) (PLGA) nanofibers incorporated with hyaluronic acid oligosaccharide-collagen mineralized microparticles (labeled oHA-Col/HAP) to guide the cell-specific orientation and osseointegration in bone healing. The aligned nanofibers were successfully prepared by a custom-made rotating mandrel with separating railings and HAs-Col/HAP mineralized microparticles were uniformly distributed in the composite scaffolds that acted as temporary templates for bone remodeling. The morphology, physicochemical properties and tensile strength of the scaffolds were characterized, the cell responses and in vivo biocompatibility and biodegra
Who reads Hyaluronic Acid Oligosaccharide-collagen Mineralized Product and Aligned Nanofibers with Enhanced Vascularization Properties in Bone Tissue Engineering?
It is typically read by researchers, students, and practitioners in Materials Science.
- Author
- Liling Liu; Weibin Jia; Yuanmeng Zhou; Hang Zhou; Meng Liu; Min Li; Xiuli Zhang; Guofeng Gu; Zonggang Chen
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Materials Science (Physical Sciences)