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Changes in Immunological Parameters and Umbilical Blood Flow in Pregnant Women During Exacerbation of Chronic Bronchitis Associated with Cytomegalovirus Infection by L. G. Nakhamchen; V. P. Kolosov; I. N. Gorikov; I. A. Andrievskaya; N. A. Ishutina; A. N. Odireev; A. V. Bushmanov; T. V. Smirnova; E. I. Karapetyan is a Medicine article available to read on EtoBox.
What is Changes in Immunological Parameters and Umbilical Blood Flow in Pregnant Women During Exacerbation of Chronic Bronchitis Associated with Cytomegalovirus Infection about?
Aim. To evaluate changes in immunological parameters and umbilical blood flow in pregnant women with exacerbation of chronic bronchitis associated with cytomegalovirus infection (CMVI).Materials and methods. The concentration of secretory immunoglobulin A (sIgA), immunoglobulin E (IgE), circulating immune complexes (CIC), interleukin- 6 (IL-6), interleukin-4 (IL-4) and systolic-diastolic ratio (SDR) in the umbilical artery was studied in 80 women with exacerbation of chronic bronchitis in the second trimester of pregnancy, uncomplicated and complicated by the acute phase of CMVI. The first group was represented by 30 women with cytomegalovirus seronegative physiological pregnancy; the second – 25 patients with exacerbation of chronic bronchitis caused by reactivation of CMVI, complicated by the development of chronic compensated placental insufficiency (CCPI); the third – 25 women with chronic simple bronchitis in the acute stage in the setting of the acute phase of CMVI, initiating the formation of chronic subcompensated placental insufficiency (CSPI) at 30-34 weeks of gestation.Results. In the first group, the concentration of sIgA in blood serum was 4.3±0.26 mg/L, IgE – 3.64±0.2
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- Author
- L. G. Nakhamchen; V. P. Kolosov; I. N. Gorikov; I. A. Andrievskaya; N. A. Ishutina; A. N. Odireev; A. V. Bushmanov; T. V. Smirnova; E. I. Karapetyan
- Publisher
- Far Eastern Scientific Center Of Physiology and Pathology of Respiration
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)