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Changes in Population Immunity Against Infection and Severe Disease From Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variants in the United States Between December 2021 and November 2022 by Fayette Klaassen; Melanie H Chitwood; Ted Cohen; Virginia E Pitzer; Marcus Russi; Nicole A Swartwood; Joshua A Salomon; Nicolas A Menzies is a Medicine article available to read on EtoBox.
What is Changes in Population Immunity Against Infection and Severe Disease From Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variants in the United States Between December 2021 and November 2022 about?
## Abstract ## Background Although a substantial fraction of the US population was infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during December 2021–February 2022, the subsequent evolution of population immunity reflects the competing influences of waning protection over time and acquisition or restoration of immunity through additional infections and vaccinations. ## Methods Using a Bayesian evidence synthesis model of reported coronavirus disease 2019 (COVID-19) data (diagnoses, hospitalizations), vaccinations, and waning patterns for vaccine- and infection-acquired immunity, we estimate population immunity against infection and severe disease from SARS-CoV-2 Omicron variants in the United States, by location (national, state, county) and week. ## Results By 9 November 2022, 97% (95%–99%) of the US population were estimated to have prior immunological exposure to SARS-CoV-2. Between 1 December 2021 and 9 November 2022, protection against a new Omicron infection rose from 22% (21%–23%) to 63% (51%–75%) nationally, and protection against an Omicron infection leading to severe disease increased from 61% (59%–64%) to 89% (83%–92%). Increasing first boost
Who reads Changes in Population Immunity Against Infection and Severe Disease From Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variants in the United States Between December 2021 and November 2022?
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- Author
- Fayette Klaassen; Melanie H Chitwood; Ted Cohen; Virginia E Pitzer; Marcus Russi; Nicole A Swartwood; Joshua A Salomon; Nicolas A Menzies
- Publisher
- Oxford University Press
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)