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The effect of AC electric field on the dynamics of a vesicle under shear flow in the small deformation regime by Sinha, Kumari Priti; Thaokar, Rochish M is a scholarly article available to read on EtoBox.

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Vesicles or biological cells under simultaneous shear and electric field can be encountered in dielectrophoretic devices or devices used for continuous flow electrofusion or electroporation. In this work, the dynamics of a vesicle subjected to simultaneous shear and uniform AC electric field is investigated in the small deformation limit. The coupled equations for vesicle orientation and shape evolution are derived theoretically and the resulting nonlinear equations are handled numerically to generate relevant phase diagrams that demonstrate the effect of electrical parameters on the different dynamical regimes such as tank-treading (TT), trembling (TR), and tumbling (TU). It is found that while the electric Mason number (Mn) which represents the relative strength of the electrical forces to the shear forces, promotes TT regime, the response itself is found to be sensitive to the applied frequency as well as the conductivity ratio. While higher outer conductivity promotes orientation along the flow axis, orientation along the electric field is favoured when the inner conductivity is higher. Similarly, a switch of orientation from the direction of the electric field to the direction

Author

Sinha, Kumari Priti; Thaokar, Rochish M

Published

2018

Language

EN