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This study investigates the role of autophagy mediated by the TSC1/mTOR signaling pathway in thiram-induced tibial dyschondroplasia (TD) in broiler chickens. Results indicate that thiram exposure inhibits mTOR signaling and promotes autophagy, leading to impaired chondrocyte growth and bone development. The findings suggest that targeting the mTOR pathway may provide a potential strategy for preventing TD in poultry.

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a1518173810

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EN