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Synthesis of the naringinase inhibitors l-swainsonine and related 6-C-methyl-l-swainsonine analogues: (6R)-C-methyl-l-swainsonine is a more potent inhibitor of l-rhamnosidase by an order of magnitude than l-swainsonine by Anders E. Håkansson; Jeroen van Ameijde; Graeme Horne; Robert J. Nash; Mark R. Wormald; Atsushi Kato; Gurdyal S. Besra; Sudagar Gurcha; George W.J. Fleet is a Chemistry article available to read on EtoBox.
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Efficient syntheses are reported of the a-L L-rhamnosidase inhibitors L L-swainsonine [(1R,2S,8S,8aS)-octahydroindolizine-1,2,8-triol], (6R)-C-methyl-L L-swainsonine (1R,2S,6R,8S,8aS)-6-methyloctahydro-indolizine-1,2
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- Author
- Anders E. Håkansson; Jeroen van Ameijde; Graeme Horne; Robert J. Nash; Mark R. Wormald; Atsushi Kato; Gurdyal S. Besra; Sudagar Gurcha; George W.J. Fleet
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0040-4039)
- Published
- 2008
- Language
- EN
- Field
- Chemistry (Physical Sciences)