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Can I read Rotational effect and dosimetric impact: HDMLC vs 5-mm MLC leaf width in single isocenter multiple metastases radiosurgery with Brainlab ElementsTM on EtoBox?

Rotational effect and dosimetric impact: HDMLC vs 5-mm MLC leaf width in single isocenter multiple metastases radiosurgery with Brainlab ElementsTM by Carlos Daniel Venencia; José Alejandro Rojas-López; Rogelio Manuel Díaz Moreno; Silvia Zunino is a Medicine article available to read on EtoBox.

What is Rotational effect and dosimetric impact: HDMLC vs 5-mm MLC leaf width in single isocenter multiple metastases radiosurgery with Brainlab ElementsTM about?

Purpose: To analyse the impact of multileaf collimator (MLC) leaf width in multiple metastases radiosurgery (SRS) considering the target distance to isocenter and rotational displacements. Methods: Ten plans were optimised. The plans were created with Elements Multiple Mets SRS v2•0 (Brainlab AG, Munchen, Germany). The mean number of metastases per plan was 5 ± 2 [min 3, max 9], and the mean volume of gross tumour volume (GTV) was 1 Planning target volume margin criterion was based on GTV-isocenter distance and target dimensions. Plans were performed using 6 MV with high-definition MLC (HDMLC) and reoptimised using 5-mm MLC (MLC-5). Plans were compared using Paddick conformity index (PCI), gradient index, monitor units , volume receiving half of prescription isodose (PIV 50 ), maximum dose to brainstem, optic chiasm and optic nerves, and V12Gy, V10Gy and V5Gy for healthy brain were analysed. The maximum displacement due to rotational combinations was optimised by a genetic algorithm for both plans. Plans were reoptimised and compared using optimised margin. Results: HDMLC plans had better conformity and higher dose falloff than MLC-5 plans. Dosimetric differences were statistically

Who reads Rotational effect and dosimetric impact: HDMLC vs 5-mm MLC leaf width in single isocenter multiple metastases radiosurgery with Brainlab ElementsTM?

It is typically read by researchers, students, and practitioners in Medicine.

Author
Carlos Daniel Venencia; José Alejandro Rojas-López; Rogelio Manuel Díaz Moreno; Silvia Zunino
Publisher
Cambridge University Press (CUP)
Published
2022
Language
EN
Field
Medicine (Health Sciences)

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