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Can I read A Systematic Review and Meta-analysis of Clinical Outcomes of Small Gauge Vitrectomy with or Without Intravitreal Antivascular Endothelial Growth Factor Agents Pretreatment for Proliferative Diabetic Retinopathy on EtoBox?
A Systematic Review and Meta-analysis of Clinical Outcomes of Small Gauge Vitrectomy with or Without Intravitreal Antivascular Endothelial Growth Factor Agents Pretreatment for Proliferative Diabetic Retinopathy by Minghang Pei; Xinyu Zhao; Guangming Wan is a Medicine article available to read on EtoBox.
What is A Systematic Review and Meta-analysis of Clinical Outcomes of Small Gauge Vitrectomy with or Without Intravitreal Antivascular Endothelial Growth Factor Agents Pretreatment for Proliferative Diabetic Retinopathy about?
Background: Proliferative diabetic retinopathy (PDR) is a common visual threatening ocular disease, patients with nonclearing vitreous hemorrhage (VH), tractional retinal detachment (RD), or extensive fibrovascular proliferation are always in need for surgical treatment. Although several studies reported better surgical outcome in patients underwent surgery after anti-VEGF injection, the effect of anti-VEGF pretreatment for small gauge vitrectomy in PDR patients remains to be elucidated. Objectives: The objective of the study was to evaluate the benefits of preoperative anti-VEGF treatment in small gauge vitrectomy for PDR patients. Methods: A comprehensive literature search in PubMed, Embase, and the Cochrane Central Register of Controlled Trials was performed to identify relevant studies. Meta-analyses were performed for intraoperative (including intraoperative bleeding, endodiathermy, iatrogenic retinal breaks, surgical time, etc.) and postoperative outcome parameters (including best-corrected visual acuity (BCVA), postoperative VH, postoperative RD, etc.). Results: Ten randomized controlled trials were identified and used for comparing small gauge vitrectomy alone (344 eyes, co
Who reads A Systematic Review and Meta-analysis of Clinical Outcomes of Small Gauge Vitrectomy with or Without Intravitreal Antivascular Endothelial Growth Factor Agents Pretreatment for Proliferative Diabetic Retinopathy?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Minghang Pei; Xinyu Zhao; Guangming Wan
- Publisher
- S. Karger AG
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)