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What is Palladium-Catalyzed Kinetic Resolution of Alcohols about?

This document discusses the palladium-catalyzed aerobic oxidative kinetic resolution of secondary alcohols, focusing on the synthesis of key pharmaceutical building blocks relevant to drugs like Prozac and Singulair. The study highlights the effectiveness of the method in achieving high enantiomeric selectivity and compatibility with various functional groups. The authors demonstrate the utility of their approach through successful resolutions of diverse substrates, including amino alcohol derivatives and c

Author

J Venkat Raman

Language

EN