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Coronary thrombi develop due to endothelial damage exposing collagen and tissue factor to the bloodstream. This initiates platelet adhesion and activation of the coagulation cascade, forming thrombi. Thrombi can partially or completely occlude arteries and cause acute coronary syndromes. Natural defenses against thrombosis include antiplatelets, anticoagulants, and fibrinolytics that promote thrombus resolution. Therapies target lysis of occlusive thrombi or arresting non-occlusive thrombi to prevent progre

Author

GCY56

Language

EN