Can I read The Prognostic Value of Serum and Urine Amylase Levels and Blood Count Parameters in Assessing the Risk of Post-endoscopic Pancreatitis Development on EtoBox?

The Prognostic Value of Serum and Urine Amylase Levels and Blood Count Parameters in Assessing the Risk of Post-endoscopic Pancreatitis Development by Andrzej Jamry is a Medicine article available to read on EtoBox.

What is The Prognostic Value of Serum and Urine Amylase Levels and Blood Count Parameters in Assessing the Risk of Post-endoscopic Pancreatitis Development about?

## Introduction Detection of post-endoscopic pancreatitis (PEP) in the first hours after endoscopic retrograde cholangiopancreatography (ERCP) can limit its consequences, while excluding it can provide safe discharge of the patient. Therefore, a simple, clinically available test is needed for this purpose. ## Aim The assessment of the risk of PEP development based on serum and urine amylase levels and parameters included in blood counts 4 h after ERCP. ## Material and methods The study included 398 patients after therapeutic ERCP. Four hours after the procedure was completed, serum and urine amylase levels and blood count parameters were analysed. ## Results The optimal serum amylase level for PEP detection was 516 UI/l, with ACC = 0.94, sens. 77.8%, spec. 0.95; positive predictive value (PPV) 0.412, negative predictive value (NPV) 0.98, positive likelihood factor (LR+) 14.93, and negative likelihood factor (LR–) 0.23. The serum amylase level for exclusion of PEP was 184 UI/l with ACC 0.79, sens. 0.83, spec. 0.79, PPV 0.16, NPV 0.99, and LR– 0.21. The optimal urine amylase level for detection and exclusion (based on Youden index) was 575 UI/l, sens. 83.33%, spec. 81.3%, PPV 0.172,

Who reads The Prognostic Value of Serum and Urine Amylase Levels and Blood Count Parameters in Assessing the Risk of Post-endoscopic Pancreatitis Development?

Author

Andrzej Jamry

Publisher

Termedia Sp. z.o.o.

Published

2021

Language

EN

Field

Medicine (Health Sciences)