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Lapatinib by anon_183693416 is a document available to read on EtoBox.

What is Lapatinib about?

1) The document discusses how the drug lapatinib can reverse multidrug resistance in cancer cells by inhibiting two ATP-binding cassette transporters, ABCB1 and ABCG2. 2) Experiments showed that lapatinib increased the sensitivity of cancer cells overexpressing ABCB1 and ABCG2 to certain drugs, inhibited the transport functions of the two transporters, and enhanced the anticancer effects of other drugs. 3) The authors conclude that lapatinib can reverse multidrug resistance by specifically inhibiting the

Author

anon_183693416

Language

EN