Can I read Pharmacokinetics of Ceftiofur in Llamas and Alpacas on EtoBox?

Pharmacokinetics of Ceftiofur in Llamas and Alpacas by M. L. Drew; L. Johnson; D. Pugh; C. B. Navarre; I. T. Taylor; A. L. Craigmill is a Medicine article available to read on EtoBox.

What is Pharmacokinetics of Ceftiofur in Llamas and Alpacas about?

Pharmacokinetic studies of antibiotics in South American camelids are uncommon, therefore drugs are often administered to llamas and alpacas based on dosages established in other domestic species. The disposition of ceftiofur sodium was studied in llamas following intramuscular administration and in alpacas following intravenous and intramuscular administration. Eleven adult llamas were given ceftiofur sodium by intramuscular injection. Each animal received either a standard dose of 2.2 mg/kg or an allometrically scaled dose ranging from 2.62 to 2.99 mg/kg in a crossover design. Ten adult alpacas were given ceftiofur sodium by intravenous and intramuscular injections. Each animal received a standard dosage of 1 mg/kg or an allometrically scaled dose ranging from 1.27 to 1.44 mg/kg i.v., and 1.31–1.51 mg/kg i.m. Blood samples were collected at 0, 0.25, 0.5, 1, 2, 4, 8, 12, 24, 36, 48, and 72 h after administration of the ceftiofur. Pharmacokinetic parameters of ceftiofur in llamas and alpacas were similar following i.m. dosing at both dose levels. The only differences noted were in the total __AUC__ between dose levels, but the __AUC__/dose values were not different. A sequence effe

Who reads Pharmacokinetics of Ceftiofur in Llamas and Alpacas?

Author

M. L. Drew; L. Johnson; D. Pugh; C. B. Navarre; I. T. Taylor; A. L. Craigmill

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0140-7783)

Published

2004

Language

EN

Field

Medicine (Health Sciences)