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What is Homologous vs Non-Homologous Recombination about?

1. DNA can be damaged through natural polymerase errors, endogenous sources like oxidation, and exogenous sources like radiation or chemicals. This damage can lead to mutations if unrepaired. 2. There are several mechanisms for repairing DNA damage, including direct repair, base excision repair, nucleotide excision repair, and mismatch repair. Homologous recombination is also used for repairing double-stranded breaks. 3. Failure to properly repair DNA damage can lead to genetic abnormalities and diseases

Author

Leroy Cheng

Language

EN