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Saturation biopsy improves preoperative Gleason scoring of prostate cancer by Philip Kahl; Susanne Wolf; Alexander Adam; Lukas Carl Heukamp; Jörg Ellinger; Roland Vorreuther; Gerold Solleder; Reinhard Buettner is a Medicine article available to read on EtoBox.

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We evaluated the differences between conventional needle biopsy (CB) and saturation biopsy (SB) techniques with regard to the prediction of Gleason score, tumor stage, and insignificant prostate cancer. Data from a total number of 240 patients were analyzed. The main group, consisting of 185 patients, was diagnosed according to a saturation prostate needle biopsy protocol (SB), by which more than 12 cores were taken per biopsy. The control group was diagnosed using CB, by which 12 or less than 12 cores were taken per biopsy (n 1⁄4 55). In the main group, the Gleason score of the biopsy was confirmed in 19.5%, in the control group in 23.5% according to the prostatectomy specimen (p 1⁄4 0.50). Upgrading after the operation was found in 56.7% in the main group and in 60% in the control group (p 1⁄4 0.24). Downgrading after the operation was found in 23.9% in the main group and in 16.3% in the control group (p 1⁄4 0.24). If the Gleason score of the postoperative specimens differed by only one point from the biopsy, we considered this a minor deviation. In the main group, 59% of the carcinomas were preoperatively classified correctly or revealed minor deviation in Gleason scores. In con

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Author

Philip Kahl; Susanne Wolf; Alexander Adam; Lukas Carl Heukamp; Jörg Ellinger; Roland Vorreuther; Gerold Solleder; Reinhard Buettner

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0344-0338)

Published

2009

Language

EN

Field

Medicine (Health Sciences)