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Can I read Cerebral Asymmetry and Behavioral Lateralization in Rats Chronically Lacking n-3 Polyunsaturated Fatty Acids on EtoBox?
Cerebral Asymmetry and Behavioral Lateralization in Rats Chronically Lacking n-3 Polyunsaturated Fatty Acids by Sylvie Vancassel; Sabah Aïd; Fabien Pifferi; Elise Morice; Marika Nosten-Bertrand; Sylvie Chalon; Monique Lavialle is a Neuroscience article available to read on EtoBox.
What is Cerebral Asymmetry and Behavioral Lateralization in Rats Chronically Lacking n-3 Polyunsaturated Fatty Acids about?
## Background: Anatomic and functional brain lateralization underlies hemisphere specialization for cognitive and motor control, and deviations from the normal patterns of asymmetry appear to be related to behavioral deficits. studies on n-3 polyunsaturated fatty acid (pufa) deficiency and behavioral impairments led us to postulate that a chronic lack of n-3 pufa can lead to changes in lateralized behavior by affecting structural or neurochemical patterns of asymmetry in motor-related brain structures. ## Methods: We compared the effects of a chronic n-3 pufa deficient diet with a balanced diet on membrane phospholipid fatty acids composition and immunolabeling of choline acetyltransferase (chat), as a marker of cholinergic neurons, in left and right striatum of rats. lateral motor behavior was assessed by rotation and paw preference. ## Results: Control rats had an asymmetric pufa distribution with a right behavioral preference, whereas chat density was symmetrical. in deficient rats, the cholinergic neuron density was 30% lower on the right side, associated with a loss of pufa asymmetry and behavior laterality. they present higher rotation behavior, and significantly more of them
Who reads Cerebral Asymmetry and Behavioral Lateralization in Rats Chronically Lacking n-3 Polyunsaturated Fatty Acids?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Sylvie Vancassel; Sabah Aïd; Fabien Pifferi; Elise Morice; Marika Nosten-Bertrand; Sylvie Chalon; Monique Lavialle
- Publisher
- Elsevier BV
- Published
- 2005
- Language
- EN
- Field
- Neuroscience (Life Sciences)