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Frequency of brain MRI abnormalities in neuromyelitis optica spectrum disorder at presentation: A cohort of Latin American patients by Edgar Carnero Contentti; Vanessa Daccach Marques; Ibis Soto de Castillo; Veronica Tkachuk; Amilton Antunes Barreira; Elizabeth Armas; Edson Chiganer; Camila de Aquino Cruz; José Luis Di Pace; Javier Pablo Hryb; Carolina Lavigne Moreira; Carmen Lessa; Omaira Molina; Monica Perassolo; Arnoldo Soto; Alejandro Caride is a Medicine article available to read on EtoBox.

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## Background: Brain magnetic resonance imaging (bmri) lesions were classically not reported in neuromyelitis optica (nmo). however, bmri lesions are not uncommon in nmo spectrum disorder (nmosd) patients. ## Objective: To report bmri characteristic abnormalities (location and configuration) in nmosd patients at presentation. ## Methods: Medical records and bmri characteristics of 79 patients with nmosd (during the first documented attack) in argentina, brazil and venezuela were reviewed retrospectively. ## Results: Bmri abnormalities were observed in 81.02% of nmosd patients at presentation. forty-two patients (53.1%) showed typical-nmosd abnormalities. we found bmri abnormalities at presentation in the brainstem/cerebellum (n = 26; 32.9%), optic chiasm (n = 16; 20.2%), area postrema (n = 13; 16.4%), thalamus/hypothalamus (n = 11; 13.9%), corpus callosum (n = 11; 13.9%), periependymal-third ventricle (n = 9; 11.3%), corticospinal tract (n = 7; 8.8%), hemispheric white matter (n = 1; 1.2%) and nonspecific areas (n = 49; 62.03%). asymptomatic bmri lesions were more common. the frequency of brain mri abnormalities did not differ between patients who were positive and negative for aqu

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Author

Edgar Carnero Contentti; Vanessa Daccach Marques; Ibis Soto de Castillo; Veronica Tkachuk; Amilton Antunes Barreira; Elizabeth Armas; Edson Chiganer; Camila de Aquino Cruz; José Luis Di Pace; Javier Pablo Hryb; Carolina Lavigne Moreira; Carmen Lessa; Omaira Molina; Monica Perassolo; Arnoldo Soto; Alejandro Caride

Publisher

Elsevier BV

Published

2017

Language

EN

Field

Medicine (Health Sciences)