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Can I read Female Genital‐Tract HIV Load Correlates Inversely with Lactobacillus Species but Positively with Bacterial Vaginosis and Mycoplasma hominis on EtoBox?
Female Genital‐Tract HIV Load Correlates Inversely with Lactobacillus Species but Positively with Bacterial Vaginosis and Mycoplasma hominis by Beverly E. Sha; M. Reza Zariffard; Qiong J. Wang; Hua Y. Chen; James Bremer; Mardge H. Cohen; Gregory T. Spear is a Medicine article available to read on EtoBox.
What is Female Genital‐Tract HIV Load Correlates Inversely with Lactobacillus Species but Positively with Bacterial Vaginosis and Mycoplasma hominis about?
Background. Bacterial vaginosis (BV) is associated with human immunodeficiency virus (HIV) acquisition. We examined the association between BV and BV-associated bacteria and expression of HIV in the female genital tract. Methods. HIV RNA, lactobacilli, Gardnerella vaginalis, and Mycoplasma hominis in cervicovaginal lavage (CVL) samples were quantified by polymerase chain reaction (PCR). Gynecologic evaluation included Nugent score assessment, Amsel criteria assessment, detection of other genital-tract infections, and dysplasia grading. CD4 cell count, plasma HIV RNA level, and antiretroviral history were obtained. Results. A total of 203 CVL samples from women with Nugent scores of 7-10 (BV group) and 203 samples from women with Nugent scores of 0-3 (no-BV group) were matched by plasma HIV RNA level and analyzed. After controlling for plasma HIV RNA level and Nugent score in univariate analyses, we found that G. vaginalis and M. hominis bacterial counts, Candida vaginitis, and herpes simplex virus (HSV) were positively associated with CVL HIV RNA levels. In multivariate analysis, only lactobacilli bacterial counts ( ; inverse association), P p .006 M. hominis bacterial counts ( ; p
Who reads Female Genital‐Tract HIV Load Correlates Inversely with Lactobacillus Species but Positively with Bacterial Vaginosis and Mycoplasma hominis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Beverly E. Sha; M. Reza Zariffard; Qiong J. Wang; Hua Y. Chen; James Bremer; Mardge H. Cohen; Gregory T. Spear
- Publisher
- Oxford University Press (OUP)
- Published
- 2005
- Language
- EN
- Field
- Medicine (Health Sciences)