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Bipolar disorder. II: Personality and age of onset by Christer Engström; Sven Brändström; Sören Sigvardsson; Robert Cloninger; Per‐Olof Nylander is a Medicine article available to read on EtoBox.

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**Objectives:** The aim of this study was to examine whether personality i.e. temperament and character interacts with age of onset in bipolar disorder. **Methods:** Bipolar patients were recruited among in‐ and outpatients from lithium dispensaries of northern Sweden. Patients were diagnosed according to DSM‐IV criteria for bipolar disorder type I and II. Temperament and Character Inventory (TCI) was used for measuring personality. TCI was administered to 100 lithium treated bipolar patients and 100 controls. **Results:** Treatment response was significantly lower (p = 0.005) in patients with early onset compared with late onset. Family history (p = 0.013) and suicide attempts (p = 0.001) were also significantly more common in patients with early onset. Further, patients with early onset were significantly higher (p = 0.045) in the temperament factor harm avoidance (HA) than patients with late onset, but the difference was weak. Patients with early onset had more fear of uncertainty (HA2; p = 0.022) and were more shy (HA3; p = 0.030). Bipolar I patients showed similar results as those in the total bipolar group (I and II), with significantly higher HA (p = 0.019, moderate differen

Who reads Bipolar disorder. II: Personality and age of onset?

Author

Christer Engström; Sven Brändström; Sören Sigvardsson; Robert Cloninger; Per‐Olof Nylander

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 1398-5647)

Published

2003

Language

EN

Field

Medicine (Health Sciences)