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Can I read High-Density Lipoproteins: Effects on Vascular Function and Role in the Immune Response on EtoBox?
High-Density Lipoproteins: Effects on Vascular Function and Role in the Immune Response by Arash Haghikia; Ulf Landmesser is a Medicine article available to read on EtoBox.
What is High-Density Lipoproteins: Effects on Vascular Function and Role in the Immune Response about?
The focus in studies of high-density lipoproteins was on their capacity to remove excess cholesterol and deliver it to the liver. Other functions and vascular effects have been described. Clinical trials and translational/genetic studies have led to a refined understanding of the role of high-density lipoprotein; it is likely not a causal cardiovascular risk factor. In healthy subjects, it limits lipid oxidation, protects endothelial cell functions/integrity, and exerts antiinflammatory/antiapoptotic effects. In patients with coronary disease or diabetes, it undergoes modifications/remodeling, resulting in dysfunctional high-density lipoprotein. We summarize recent findings about the regulation of its function and discuss the clinical implications.
Who reads High-Density Lipoproteins: Effects on Vascular Function and Role in the Immune Response?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Arash Haghikia; Ulf Landmesser
- Publisher
- Elsevier BV
- Published
- 2018
- Language
- EN
- Field
- Medicine (Health Sciences)