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The MOMPOD trial investigated the effects of adding metformin to insulin treatment for pregnant individuals with preexisting type 2 diabetes or gestational diabetes diagnosed early in pregnancy. The study found no significant reduction in composite adverse neonatal outcomes between the metformin and placebo groups, although there was a noted decrease in the incidence of large-for-gestational-age infants in the metformin group. The trial was halted due to futility in detecting a significant difference in the
- Author
- abdullah shamshir
- Language
- EN