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Can I read Tyrosine Kinases: Modular Signaling Enzymes with Tunable Specificities on EtoBox?
Tyrosine Kinases: Modular Signaling Enzymes with Tunable Specificities by Kevan M. Shokat is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Tyrosine Kinases: Modular Signaling Enzymes with Tunable Specificities about?
Cytoplasmic tyrosine kinases are composed of modular domains; one (SH1) has catalytic activity, the other two (SH2 and SH3) do not. Kinase specificity is largely determined by the binding preferences of the SH2 domain. Attaching the SH1 domain to a new SH2 domain, via protein-protein association or mutation, can thus dramatically change kinase function.
Who reads Tyrosine Kinases: Modular Signaling Enzymes with Tunable Specificities?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Kevan M. Shokat
- Publisher
- Elsevier Science; Elsevier ; Cell Press; Elsevier BV (ISSN 1074-5521)
- Published
- 1995
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)