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What is Catalytic Grignard-Type C-H Additions about?

This chapter discusses the catalytic Grignard-type addition of aryl C-H bonds to C=O and C=N bonds, highlighting its advantages over classical Grignard reactions, such as improved atom economy and reduced waste. It reviews recent advancements categorized by different metal catalysts, including iridium, rhenium, manganese, and rhodium, and emphasizes the challenges and strategies in achieving effective C-H activation. The chapter also showcases applications in synthesizing heterocycles and other valuable com

Author

Niisama

Language

EN