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Aeroallergens in Atopic Dermatitis and Chronic Urticaria by Albert C. Chong; Won Jong Chwa; Peck Y. Ong is a Medicine article available to read on EtoBox.

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## Purpose of review: While aeroallergens are a well-established trigger of asthma and allergic rhinitis, their role in allergic skin diseases such as atopic dermatitis and chronic urticaria remains controversial. this paper reviews the pathophysiology and clinical evidence for aeroallergens in these allergic skin diseases and summarizes current strategies for evaluation and management. ## Recent findings: Current evidence implicates aeroallergens as triggers of cutaneous reactions in atopic dermatitis. direct skin contact is the likely route of trigger. aeroallergens may also trigger chronic urticaria, though mechanistic studies are limited. these allergens may cross the skin barrier and directly trigger neurons to release substance p, resulting in mast cell degranulation and dumping of histamine and prostaglandin d2. many studies link aeroallergen sensitization to chronic urticaria, and case reports suggest the utility of avoidance strategies. the role of aeroallergens as a trigger is clear in atopic dermatitis and becoming emergent in chronic urticaria. skin prick testing or serum-specific immunoglobulin e testing may be used to determine sensitivities. management at this time c

Who reads Aeroallergens in Atopic Dermatitis and Chronic Urticaria?

Author

Albert C. Chong; Won Jong Chwa; Peck Y. Ong

Publisher

Springer Science and Business Media LLC

Published

2022

Language

EN

Field

Medicine (Health Sciences)