About this Immunology and Microbiology article
Sendai virus stimulates chemiluminescence in mouse T and B lymphocytes by Ernst Peterhans; Janice Mundy; Christopher R. Parish is a Immunology and Microbiology article available to read on EtoBox.
## Abstract Mouse spleen cells emit a burst of chemiluminescence (CL) starting within a few seconds on infection with Sendai virus. We have analyzed the cell types responsible for the generation of CL in the spleen cell population. Cell suspensions, treated with iron carbonyl powder to remove adherent cells, showed similar CL compared to untreated spleen cells suggesting that lymphocytes, rather than phagocytic cells, were responsible for CL generation. Furthermore, killing of T lymphocytes with anti‐ Thy‐1.2 antibody and complement, and removal of Ig^+^ cells from the cell population, respectively, showed that both T and B lymphocytes are active in CL generation. The results suggest that changes in lymphocyte metabolism occur within the first few minutes of cell‐virus contact.
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- Author
- Ernst Peterhans; Janice Mundy; Christopher R. Parish
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Ltd.; Wiley (ISSN 0014-2980)
- Published
- 1980
- Language
- EN
- Field
- Immunology and Microbiology (Life Sciences)