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Anemia Diagnosis and Therapy in Malignant Diseases: Implementation of Guidelines—a Representative Study by Hartmut Link; Markus Kerkmann; Laura Holtmann; Markus Detzner is a Medicine article available to read on EtoBox.

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## Purpose Anemia in cancer should be diagnosed and treated according to guideline recommendations. The implementation of ESMO and German guidelines and their effect on anemia correction was analyzed. ## Methods This retrospective epidemiological study, representative for Germany, analyzed data on anemia management of cancer patients with anemia ≥ grade 2. The Guideline Adherence Score (GLAD) for diagnosis (GLAD-D) and therapy (GLAD-T) was defined as follows: 2 points for complete, 1 point for partial, 0 point for no adherence. ## Results Data were analyzed for 1046 patients. Hb levels at diagnosis of anemia were 8–10 g/dL in 899 (85.9%) patients, 7–8 g/dL in 92 (8.7%), and < 7 g/dL (5.0%) in 52. Transferrin saturation was determined in 19% of patients. Four hundred fifty-six patients received RBC (43.6%), 198 (18.9%) iron replacement, 106 (10.1%) ESA, and 60 (5.7%) vitamin B12 replacement. 60.6% of patients receiving iron replacement were treated intravenously and 39.4% were treated orally. Two hundred eighty-eight (36.6%) of 785 patients receiving transfusions had no guideline-directed indication. GLAD-D was 2 in 310 patients (29.6%), 1 in 168 (16.1%), and 0 in 568 (54.3%). GLAD-

Who reads Anemia Diagnosis and Therapy in Malignant Diseases: Implementation of Guidelines—a Representative Study?

Author

Hartmut Link; Markus Kerkmann; Laura Holtmann; Markus Detzner

Publisher

Springer Science and Business Media LLC

Published

2024

Language

EN

Field

Medicine (Health Sciences)