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Trends in the Microbiological Spectrum of Nonviral Keratitis at a Single Tertiary Care Ophthalmic Hospital in India: A Review of 30 years by Joveeta Joseph; Roshini Karoliya; Esther Sheba; Savitri Sharma; Bhupesh Bagga; Prashant Garg is a Medicine article available to read on EtoBox.
What is Trends in the Microbiological Spectrum of Nonviral Keratitis at a Single Tertiary Care Ophthalmic Hospital in India: A Review of 30 years about?
## Purpose: The aims of this study were to assess the trends in microorganisms from patients with infectious keratitis and to assess their antibiogram patterns at a tertiary eye care center in india. ## Methods: In this retrospective observational case series, microbiological records of all corneal ulcers were reviewed from 1991 to 2020 and assessed for trends in keratitis and antibiotic susceptibility using the χ2 test. ## Results: Of the total of 51,747 patients, 51.13% were culture positive. a decrease in bacteria was noted from 56% to 38%, with a parallel increase in fungal isolates from 24% to 51%. gram-positive bacteria accounted for 70.8% of the total bacteria, a trend in rise of streptococcus pneumoniae (31%) and a decreasing trend in prevalence of staphylococcus epidermidis was observed over 30 years. pseudomonas aeruginosa (55.5%) was the most prevalent gram-negative pathogen, whereas fusarium spp. (33.1%) and aspergillus spp. (32.4%) were the most common fungal isolates. the susceptibility of gram-positive organisms to cefazolin decreased from 95.5% to 66% (p = 0.0001), amikacin from 88% to 55% (p= 0.0001), and vancomycin from 98.9% to 90.7% (p < 0.05). a similar decreas
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- Author
- Joveeta Joseph; Roshini Karoliya; Esther Sheba; Savitri Sharma; Bhupesh Bagga; Prashant Garg
- Publisher
- Ovid Technologies (Wolters Kluwer Health)
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)