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This preprint discusses a study on membrane protein-lipid interactions, specifically focusing on Aquaporin Z (AqpZ) and its selectivity for cardiolipins using native mass spectrometry and molecular dynamics simulations. The research identifies specific lipid binding sites on AqpZ and evaluates the selectivity of various lipids at these sites, revealing that AqpZ preferentially binds cardiolipins at certain locations. The findings enhance the understanding of how lipids influence the structure and function o

Author

Julio Cesar Bustinza Yepez

Language

EN