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Non-hodgkin's lymphoma presenting with biliary tract obstruction. A discussion of seven patients and a review of the literature by Panos Fidias; Robert W. Carey; Michael L. Grossbard is a Medicine article available to read on EtoBox.

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## Background: Biliary tract obstruction is a rare manifestation of non-hodgkin's lymphoma (nhl). because of the small numbers of patients studied, management of this condition has been inconsistent. most patients have been treated with biliary diversion, and doxorubicin frequently has been withheld from initial therapy. ## Methods: Seven patients with nhl presenting with malignant biliary tract obstruction were identified at the massachusetts general hospital. relevant clinical characteristics, laboratory values, treatment, and outcome are reported for all patients. thirty-eight additional patients were identified through a medline search; and the management and results of the patients reported here are discussed with reference to those patients. ## Results: Biliary tract obstruction was the presenting symptom in 0.8% of the patients with nhl. bilirubin values at presentation ranged from 5.0-23.2 mg/dl. one patient had localized pancreatic lymphoma. four of the seven patients had advanced-stage disease. the tumor was intermediate or high grade in five patients. four patients underwent placement of a biliary stent or drainage catheter. six patients received combination chemotherapy

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Author

Panos Fidias; Robert W. Carey; Michael L. Grossbard

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)

Published

1995

Language

EN

Field

Medicine (Health Sciences)