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Geographic differences in invasive and in situ breast cancer incidence according to precise geographic coordinates, Connecticut, 1991–95 by David I. Gregorio; Martin Kulldorff; Leah Barry; Holly Samociuk is a Medicine article available to read on EtoBox.

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## Abstract To evaluate geographical variation of invasive and __in situ__ breast cancer incidence rates using precise geographical coordinates for place of residence at diagnosis, latitude‐longitude coordinates pertaining to 10,601 invasive and 1,814 __in situ__ breast cancers for Connecticut women, 1991–95, were linked to US Census information on the 2,905State census block groups. A spatial scan statistic was used to detect geographic excess or deficits in incidence and test the statistical significance of results, without prior assumptions about the size or location of such areas. The age adjusted invasive cancer incidence rate was 165.3/100,000 women/year. The spatial scan statistic identified 3 places with significantly low incidence rates and 4 places where rates were significantly high. The most probable location of low incidence was rural northeastern Connecticut where risk of disease, relative to elsewhere around the state, was 0.70 (__p__ = 0.0001); the most probable place of elevated incidence was north central Connecticut where a relative risk of 1.34 (__p__ = 0.002) was observed. Incidence of __in situ__ disease was estimated to be significantly high for north central

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Author
David I. Gregorio; Martin Kulldorff; Leah Barry; Holly Samociuk
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square; Test accounts (ISSN 0020-7136)
Published
2002
Language
EN
Field
Medicine (Health Sciences)

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