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Characterization of NT‐proBNP in a large cohort of COVID‐19 patients by Juan Caro‐Codón; Juan R. Rey; Antonio Buño; Angel M. Iniesta; Sandra O. Rosillo; Sergio Castrejon‐Castrejon; Laura Rodriguez‐Sotelo; Luis A. Martinez; Irene Marco; Carlos Merino; Lorena Martin‐Polo; Jose M. Garcia‐Veas; Marcel Martinez‐Cossiani; Luis Gonzalez‐Valle; Alicia Herrero; Esteban López‐de‐Sa; Jose L. Merino; CARD‐COVID Investigators is a Medicine article available to read on EtoBox.
What is Characterization of NT‐proBNP in a large cohort of COVID‐19 patients about?
## Aims: Extensive research regarding the association of troponin and prognosis in coronavirus disease 2019 (covid-19) has been performed. however, data regarding natriuretic peptides are scarce. n-terminal pro b-type natriuretic peptide (nt-probnp) reflects haemodynamic stress and has proven useful for risk stratification in heart failure (hf) and other conditions such as pulmonary embolism and pneumonia. we aimed to adequately characterize nt-probnp concentrations using a large cohort of patients with covid-19, and to investigate its association with prognosis. ## Methods and results: Consecutive patients with confirmed severe acute respiratory syndrome coronavirus 2 (sars-cov-2) infection and available nt-probnp determinations, from march 1st to april 20th, 2020 who completed at least 1-month follow-up or died, were studied. of 3080 screened patients, a total of 396 (mean age 71.8 ± 14.6 years, 61.1% male) fulfilled all the selection criteria and were finally included, with a median follow-up of 53 (18-62) days. of those, 192 (48.5%) presented nt-probnp levels above the recommended cut-off for the identification of hf. however, only 47 fulfilled the clinical criteria for the dia
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- Author
- Juan Caro‐Codón; Juan R. Rey; Antonio Buño; Angel M. Iniesta; Sandra O. Rosillo; Sergio Castrejon‐Castrejon; Laura Rodriguez‐Sotelo; Luis A. Martinez; Irene Marco; Carlos Merino; Lorena Martin‐Polo; Jose M. Garcia‐Veas; Marcel Martinez‐Cossiani; Luis Gonzalez‐Valle; Alicia Herrero; Esteban López‐de‐Sa; Jose L. Merino; CARD‐COVID Investigators
- Publisher
- Wiley
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)