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Changes in the Indications for Living Donor Liver Transplantation: Single-institution Experience of 3,145 Cases Over 10 Years by Sang-Hyun Kang; Shin Hwang; Chul-Soo Ahn; Ki-Hun Kim; Deok-Bog Moon; Tae-Yong Ha; Gi-Won Song; Dong-Hwan Jung; Gil-Chun Park; Jung-Man Namgoong; Young-In Yoon; Hui-Dong Cho; Jae-Hyun Kwon; Yong-Kyu Chung; Jin-Uk Choi; Sung-Gyu Lee is a Medicine article available to read on EtoBox.
What is Changes in the Indications for Living Donor Liver Transplantation: Single-institution Experience of 3,145 Cases Over 10 Years about?
## Background To understand the changing demands and recent trends in the indications for living donor liver transplantation (LDLT), the present study aimed to analyze the indications for LDLT performed in a high-volume transplantation center over 10 years. ## Methods The liver transplantation database at our institution was searched to identify patients who underwent LDLT during a 10-year period from January 2008 to December 2017. The study subjects (n=3,145) were divided into two groups: adult patients (n=3,019, 92.7%) and pediatric patients (n=126, 3.9%). ## Results In the adult recipients, the primary diagnoses were hepatitis B virus (HBV)-associated liver cirrhosis (n=1,898, 62.9%), alcoholic liver disease (n=482, 16.0%), hepatitis C virus-associated cirrhosis (n=203, 6.7%), acute liver failure (n=127, n=4.2%), and other diseases (n=157, 5.2%). The mean Model for End-Stage Liver Disease score was 15.6±8.8 (range, 6–40). The proportion of patients with HBV-associated liver disease gradually decreased, but the proportion of those with alcoholic liver disease increased. Hepatocellular carcinoma (HCC) was diagnosed in 1,467 patients (48.6%). The mean proportion of patients with HC
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- Author
- Sang-Hyun Kang; Shin Hwang; Chul-Soo Ahn; Ki-Hun Kim; Deok-Bog Moon; Tae-Yong Ha; Gi-Won Song; Dong-Hwan Jung; Gil-Chun Park; Jung-Man Namgoong; Young-In Yoon; Hui-Dong Cho; Jae-Hyun Kwon; Yong-Kyu Chung; Jin-Uk Choi; Sung-Gyu Lee
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)