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What is Pharmaceutics 18 00693 about?

This review discusses the potential of targeting SARS-CoV-2 non-structural proteins (Nsps) for the development of next-generation small-molecule antiviral therapies. It highlights the success of existing inhibitors targeting the main protease and RNA-dependent RNA polymerase, while also emphasizing the promise of additional Nsps as therapeutic targets. The document outlines a framework for assessing these proteins based on their biological function, structural tractability, and translational properties to i

Author

research.li.ri

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EN