Can I read Molecular Basis for the Antiandrogen Withdrawal Syndrome on EtoBox?
Molecular Basis for the Antiandrogen Withdrawal Syndrome by Hiroshi Miyamoto; Mujib M. Rahman; Chawnshang Chang is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Molecular Basis for the Antiandrogen Withdrawal Syndrome about?
## Abstract In patients with prostate cancer who manifest disease progression during combined androgen blockade therapy, discontinuation of antiandrogen treatment might result in prostate‐specific antigen decline, often associated with clinical improvement. The response called antiandrogen withdrawal syndrome is thus acknowledged as a general phenomenon. However, molecular mechanisms responsible for this syndrome are not completely understood. This article outlines the proposed mechanisms, including alterations of androgen receptor gene and its coregulatory proteins and activation of the signal transduction pathway, and the potential therapeutic approaches based on the specific mechanisms. © 2003 Wiley‐Liss, Inc.
Who reads Molecular Basis for the Antiandrogen Withdrawal Syndrome?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Hiroshi Miyamoto; Mujib M. Rahman; Chawnshang Chang
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0730-2312)
- Published
- 2003
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)