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What is Optimizing PLGA-Curcumin Nanoparticles about?

The study by Ranjan et al. focuses on the formulation, optimization, and scale-up of curcumin-loaded PLGA nanoparticles for cancer therapy, achieving a successful scale-up to produce 5 g of nanoparticles with stable physicochemical properties. Using Response Surface Methodology (RSM) and Central Composite Design (CCD), the researchers optimized key formulation parameters, resulting in nanoparticles with a mean size of 158.5 nm and a drug loading of 10.32%. The findings indicate that the formulation process

Author

Zenayda Aguilar

Language

EN