About this document
Fluorimetric Assay for 4-Aminophenol in Paracetamol by Meriem Bendif is a document available to read on EtoBox.
This document describes a fluorimetric method to quantify low amounts of 4-aminophenol (4-AP), a degradation product of paracetamol, in paracetamol formulations. The method is validated by determining its linearity, precision, accuracy, range, limit of detection and limit of quantification. The validated fluorimetric method is able to assay 4-AP levels below 50 ppm in paracetamol tablets, which meets the specification limit.
- Author
- Meriem Bendif
- Language
- EN