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Mapping Quantitative Trait Loci (QTL) in sheep. III. QTL for carcass composition traits derived from CT scans and aligned with a meta-assembly for sheep and cattle carcass QTL by Colin R Cavanagh; Elisabeth Jonas; Matthew Hobbs; Peter C Thomson; Imke Tammen; Herman W Raadsma is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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## Abstract An (Awassi × Merino) × Merino single-sire backcross family with 165 male offspring was used to map quantitative trait loci (QTL) for body composition traits on a framework map of 189 microsatellite loci across all autosomes. Two cohorts were created from the experimental progeny to represent alternative maturity classes for body composition assessment. Animals were raised under paddock conditions prior to entering the feedlot for a 90-day fattening phase. Body composition traits were derived __in vivo__ at the end of the experiment prior to slaughter at 2 (cohort 1) and 3.5 (cohort 2) years of age, using computed tomography. Image analysis was used to gain accurate predictions for 13 traits describing major fat depots, lean muscle, bone, body proportions and body weight which were used for single- and two-QTL mapping analysis. Using a maximum-likelihood approach, three highly significant (LOD ≥ 3), 15 significant (LOD ≥ 2), and 11 suggestive QTL (1.7 ≤ LOD < 2) were detected on eleven chromosomes. Regression analysis confirmed 28 of these QTL and an additional 17 suggestive (__P__ < 0.1) and two significant (__P__ < 0.05) QTL were identified using this method. QTL with

Who reads Mapping Quantitative Trait Loci (QTL) in sheep. III. QTL for carcass composition traits derived from CT scans and aligned with a meta-assembly for sheep and cattle carcass QTL?

Author

Colin R Cavanagh; Elisabeth Jonas; Matthew Hobbs; Peter C Thomson; Imke Tammen; Herman W Raadsma

Publisher

BioMed Central; Springer (Biomed Central Ltd.); New York NY: Elsevier Science Pub. Co.; Les Ulis: 2000-2008; London: 2009-; Springer Science and Business Media LLC (ISSN 0999-193X)

Published

2010

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)