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Can I read Organotin Mefenamic Complexes—preparations, Spectroscopic Studies and Crystal Structure of a Triphenyltin Ester of Mefenamic Acid: Novel Anti‐tuberculosis Agents on EtoBox?
Organotin Mefenamic Complexes—preparations, Spectroscopic Studies and Crystal Structure of a Triphenyltin Ester of Mefenamic Acid: Novel Anti‐tuberculosis Agents by Dimitra Kovala‐Demertzi; Vaso Dokorou; Zbigniew Ciunik; Nikolaos Kourkoumelis; Mavroudis A. Demertzis is a Chemistry article available to read on EtoBox.
What is Organotin Mefenamic Complexes—preparations, Spectroscopic Studies and Crystal Structure of a Triphenyltin Ester of Mefenamic Acid: Novel Anti‐tuberculosis Agents about?
The triphenyltin adduct of mefenamic acid, [SnPh 3 L] (1), the monophenyltin complex [PhSnOL] n (2), and the dibutyltin complex [SnBu 2 L 2 ] (3), where HL is 2-[bis(2,3-dimethylphenyl)amino]benzoic acid (mefenamic acid), have been prepared and structurally characterized by means of vibrational, 1 H and 13 C NMR spectroscopies. The crystal structure of 1 has been determined by X-ray crystallography. X-ray analysis revealed a pseudo-pentacoordinated structure containing Ph 3 Sn coordinated to the carboxylato group. The structural distortion is a displacement from the tetrahedron toward the trigonal bipyramid. Significant CÐH±p interactions and intramolecular hydrogen bonds stabilize the structure 1. The polar imino hydrogen atom participates in intramolecular hydrogen bonds. Complex 1 is self-assembled via CÐH±p and stacking interactions. Vibrational and NMR data are discussed in terms of the crystal structure and the proposed structures for 1±3. Compounds 1 and 3 were tested for antimycobacterial activity against Mycobacterium tuberculosis H37Rv.
Who reads Organotin Mefenamic Complexes—preparations, Spectroscopic Studies and Crystal Structure of a Triphenyltin Ester of Mefenamic Acid: Novel Anti‐tuberculosis Agents?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Dimitra Kovala‐Demertzi; Vaso Dokorou; Zbigniew Ciunik; Nikolaos Kourkoumelis; Mavroudis A. Demertzis
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0268-2605)
- Published
- 2002
- Language
- EN
- Field
- Chemistry (Physical Sciences)